Remifentanil and tramadol.
نویسنده
چکیده
The lack of analgesic efficacy limits tramadol as a sole agent to treat severe pain after surgery. However, it has a relative lack of respiratory depressant and constipating effects compared with morphine and codeine, and does not share the propensity of nonsteroidal anti-inflammatory drugs to provoke asthma, gastrointestinal mucosal damage and renal impairment. It may well have a place in the management of pain after surgery, in combination with another drug, such as paracetamol, or after control of the worst of pain after surgery by a regional local anaesthetic technique.
منابع مشابه
The effects of tramadol on postoperative shivering after sevoflurane and remifentanil anesthesia
BACKGROUNDS Remifentanil has been reported to cause post-anesthetic shivering (PAS). Higher doses of remifentanil reportedly induce more intense PAS. Tramadol, a synthetic opioid that acts at multiple sites, is considered to be an effective treatment for PAS, but the evidence for its therapeutic benefit after remifentanil anesthesia is limited. We investigated the effect of tramadol on the inci...
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Critical care nurses and physicians are familiar with the principles of patient controlled analgesia and the opioid analgesics' regimens and observations necessary for pain control in the postoperative cardiac surgical patients. The objective of the study was to compare the effects of morphine, fentanyl, meperidine, remifentanil and tramadol which were administered by patient controlled analges...
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Remifentanil is a very potent ultrashort acting opioid, that is mainly used as a part of balanced anaesthesia regimens for management of intraoperative pain. Effective plasma levels of this drug can only be maintained using continuous infusions, as tissue esterases inactivate remifentanil within minutes following its application. The advantages of this specific pharmacokinetic behaviour are tha...
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BACKGROUND Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a rare neurological disorder that is caused by the production of antibodies against NMDARs. As many anaesthetic drugs interact with NMDARs and may worsen the disease and because the disease poses risks, such as cardiovascular events, hyperthermia and respiratory insufficiency, while under anaesthesia, administering anaesthesi...
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عنوان ژورنال:
- British journal of anaesthesia
دوره 81 1 شماره
صفحات -
تاریخ انتشار 1998